Easy to use kits measuring real-time energy flux, substrate utilization and mitochondrial function in living cells, without the need for expensive analysers.
Advanced high throughput disease models and assays for early prediction of drug toxicity, mitochondrial liability and mechanistic characterization.
Measure and monitor oxygen throughout the cell culture workflow. Multiplex assays for intracellular / extracellular oxygen concentration and ROS.
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Webinar REGISTER NOW! “Defining Physiological Normoxia in Cultured Cells for Translation to Animal Models and Man”
On October 25th at 7am PDT/ 3pm BST, Professor Giovanni Mann from Kings College London will lead a webinar in conjunction with Nature Publishing describing exciting new work conducted in collaboration with Luxcel Biosciences and, webinar sponsor, BMG LABTECH. Highlighting the importance of conducting in vitro research under oxygen conditions encountered in vivo, speakers will describe the tools necessary to recapitulate such conditions on the bench and will share new data describing the significant impact this has on key experimental outcomes.
Oxygen: Too Much of a Good Thing?
Oxygen is essential for life, and while we live in an environment with O2 at approximately 21%, cells in vivo experience far lower oxygen concentrations. Microelectrode measurements suggest that tissues experience oxygen concentrations between 0.2 and 10 % dependant on tissue, despite this, the vast majority of biological research is conducted at 21% O2, a hyperoxic state for almost all cell types. This can have profound implications on the metabolism and signalling of cells in vitro and may have even led to the selection of cell lines that, while capable of surviving in a hyperoxic environment, do not faithfully reflect the in vivo condition thereby widening the gap between lab bench and clinic.
Luxcel Biosciences Ltd announce world first physiologically relevant, in vitro Ischemia-Reperfusion Model
Ischemia-reperfusion (IR) injury, occurs in the body when blood supply returns to tissues after a period of oxygen and nutrient deprivation. It is an important feature of several diseases including cardiac arrest, stroke and cancer, and is a critical consideration during transplantation. While significant advances have been made in understanding IR injury, progress has been impaired by i. the absence of a method to accurately and reproducibly replicate injury conditions in vitro, and ii. tools have not been available to quantitatively measure real-time cellular oxygenation in the ischemic cells.
Tseng Hsiang Life Science Ltd Announced as the New Distribution Partner for the Taiwan Life Sciences Market
During this period of rapid growth and product development, Luxcel Biosciences Ltd is excited to announce Tseng Hsiang Life Science Ltd. as our new distribution partner for the Taiwan Life Sciences market. With over 41 years of experience in the fields of Tissue Culture, Molecular Biology, Immunology & Cell Biology, the company’s excellent reputation in Taiwanese biotech provides the perfect platform for our range of in vitro cell based assays.Taiwan is the natural choice with our growing business in the Asia Pacific region, Tseng Hsiang Co are the perfect fit for us.