Easy to use kits measuring real-time energy flux, substrate utilization and mitochondrial function in living cells, without the need for expensive analysers.
Advanced high throughput disease models and assays for early prediction of drug toxicity, mitochondrial liability and mechanistic characterisation.
Measure and monitor oxygen throughout the cell culture workflow. Multiplex assays for intracellular / extracellular oxygen concentration and ROS.
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Drug Discovery News Features Luxcel Biosciences in Special Cancer Metabolism Report
MitoXpress® Xtra – Extracellular Oxygen Consumption Assay
The MitoXpress® Xtra is our leading assay kit designed as all our kits to be highly flexible in a 96 or 384-well format for a fluorescence plate reader-based approach, utilized for the direct, real-time analysis of cellular respiration and mitochondrial function.
The easy-to-use MitoXpress® Xtra assay allows measurement of extracellular oxygen consumption rates (OCR) with whole cell populations (both adherent and suspension cells), isolated mitochondria, permeabilised cells and a wide range of 3D cultures including: tissues, small organisms, spheroids, scaffolds and matrixes.
The assay is also suitable for measurement of isolated enzymes, bacteria, yeasts and moulds.
Dr. Karl Morten University of Oxford speaks at FEBS Advanced Lecture Course on Oncometabolism
Dr. Karl Morten University of Oxford speaks at FEBS Advanced Lecture Course on Oncometabolism in June. Dr. Morten's talk “Exploring the impact of glucose concentration on the Warburg effect – utilising fluorescence plate reader-based OCR and ECAR assays” was excellent.
Dr. Morten spoke to the importance of having more physiologically relevant assays made more widely available, in order for cell biology researchers to better model in vivo situations an in vitro setting.
MetaCell, Cell Metabolism Made Easy
Led by Luxcel Biosciences, the consortium of Axiogenesis AG, BMG LABTECH GmbH and Luxcel supported by leading academic institutes Oxford University UK and Imperial College London are actively demonstrating a Gold Standard platform, comprising cell assays, disease models and services, together with high performance metabolism tests designed for use on laboratory standard instrumentation – the multi-mode microtiter plate reader.
This project funded by the EU H2020 Fast Track to Innovation initiative is called, MetaCell-TM, metabolism analysis made easy for Cell Translational Medicine.