MitoXpress® Xtra Oxygen Consumption Assay
Luxcel Biosciences' MitoXpress® Xtra Oxygen Consumption Assay allows real-time measurement of extracellular oxygen consumption of whole cells or isolated mitochondria. It is a reliable method to determine respiration rates for metabolic characterization and also to evaluate toxic effects of treatments on mitochondrial function in a high-throughput format.
MitoXpress® Xtra Oxygen Consumption Assay Kit
Real-Time Observation of Oxygen Consumption in Live Cells
Characterization of Energy Flux & Metabolic Phenotype
Figure 2: Cellular Energy Flux for HepG2 cells treated with compounds modulating the Oxygen Consumption Rate (OCR) or Extracellular Acidification Rate (ECAR), shown as a percentage relative to untreated control cells. Comparative measurements with MitoXpress® Xtra and pH-Xtra™ show the shift between mitochondrial respiration and glycolysis and the cellular control of energy (ATP; measured 1h post-treatment).