Across the world, changes in diet and lifestyle are causing a rapid increase in the instances of obesity, diabetes and related metabolic disorders. The severity of this escalating public health concern is driving an increased research focus on the mechanisms underlying these metabolic disorders, with a view to devising more effective therapeutic interventions. This work has highlighted mitochondrial dysfunction as a common theme, linked to perturbed glucose utilisation, altered fat metabolism, metabolic deregulation, and insulin resistance.

The Luxcel Biosciences range of metabolism assays facilitates convenient functional investigations of the key metabolic pathways central to these metabolic disorders across all relevant in vitro models.

Metabolism with Obesity and Diabetes