IN VITRO CELL-BASED ASSAYS
Our scientists are creating a comprehensive range of easy to use tools for the real-time analysis of mitochondrial function, cellular metabolism and hypoxia oxidative stress.
Our high performance in vitro assay kits, can be used individually or flexibly combined for multiparametric analysis, and are configured for use with all 96-well microtitre-format plates and all makes of fluorescence or TR-F plate readers. Luxcel’s in vitro assays make cellular metabolism accessible.
Current Product Range
MitoXpress® Xtra Oxygen Consumption Assay
Extracellular Oxygen Consumption Rate (OCR) for whole cells or isolated mitochondria. High-throughput assay to determine mitochondrial respiration and to evaluate toxic effects of drug treatments.
MitoXpress® Stress Test
A companion kit, which extends MitoXpress® Oxygen Consumption Assay for the additional evaluation of the main characteristics of mitochondrial function.
MitoXpress® FAO Assay
A companion kit, which extends MitoXpress® Xtra Oxygen Consumption Assay to measure Fatty Acid Oxidation. Delineate oxidation of exogenous, endogenous and non-long chain fatty acids.
pH-XtraTM Glycolysis Assay
Extracellular Acidification Rate (ECAR), providing a convenient and quantitative measure of Glycolytic Flux without the requirement to compensate for CO2 derived acidification.
pH-XtraTM Stress Test
A companion kit, which extends pH-Xtra™ Glycolysis Assay to determine cellular ability to respond to metabolic stress by modulation of glycolytic rate. Delineate basal glycolysis, glycolytic capacity, compensatory glycolysis and non-glycolytic acidification.
MitoXpress® Intra Intracellular Oxygen Assay
Determine the oxygen concentration that your cells are actually experiencing in culture. Unique oxygen-sensitive cell-penetrating nanoparticle probe, provides a quantitative assessment of intracellular oxygen concentration.